Search on: ELONGATION FACTOR 2 KINASE 
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Descriptor English:   Elongation Factor 2 Kinase 
Descriptor Spanish:   Quinasa del Factor 2 de Elongación 
Descriptor Portuguese:   Quinase do Fator 2 de Elongação 
Synonyms English:   Calcium-Calmodulin-Dependent Protein Kinase Type 3
Calmodulin-Dependent Protein Kinase III  
Tree Number:   D08.811.913.696.620.682.700.125.425
D12.644.360.100.425
D12.776.476.100.425
Definition English:   A monomeric calcium-calmodulin-dependent protein kinase subtype that specifically phosphorylates PEPTIDE ELONGATION FACTOR 2. The enzyme lacks a phosphorylatable activation domain that can respond to CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE, however it is regulated by phosphorylation by PROTEIN KINASE A and through intramolecular autophosphorylation. 
History Note English:   2008(1987) 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   52731 
Unique Identifier:   D054736 

Occurrence in VHL: 		 

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